Adipose Tissue-derived Stem Cells: The Friendly Side of a Classic Cardiovascular Foe

作者：Sanz Ruiz Ricardo; Fernandez Santos Maria Eugenia; Dominguez Munoa Marta; Ludwig Martin Ingrid; Parma Radoslaw; Sanchez Fernandez Pedro L; Fernandez Aviles Francisco^*

来源：Journal of Cardiovascular Translational Research, 2008, 1(1): 55-63.

DOI：10.1007/s12265-007-9006-9

• Stem Cells
• Cardiovascular Repair
• Adipose-derived Stem Cells
• Adipose Tissue
• APOLLO Trial
• PRECISE Trial

Recently, the existence of a population of stem cells located in the adipose tissue has been observed. Adipose-derived stem cells are able to differentiate into multiple cell lineages including cardiac myocytes. Hence, adipose-derived cells are emerging as a new source of adult stem cells for cardiovascular repair. In this review, we discuss the basic principles of adipose-derived stem cells (types and characteristics, obtention processes, immunophenotypic characterization, and cell potency), the initial experimental studies, and the currently ongoing clinical trials.

• 出版日期2008-3