摘要

The Z_ inv, a new invariant based on 3DD-curves of DNA sequence, which is simple for calculation and it approximates to the leading eigenvalues of the matrix associated with DNA sequence. The utility of our invariant is illustrated on the DNA sequence of 11 species. In this study, we use the Z_inv to analyze the phylogenetic relationships for the seven HA (H5N1) sequences of avian influenza virus.