A new synthesis of alkyl (E)-(3-dimethylamino)acrylates

作者：Robertson Jeffrey M; Jones Ian W; Kayne Kevin M; Contreras Cristina G; Witter Daniel J; Bates Robert B^*; Hall H K Jr

来源：Tetrahedron Letters, 2011, 52(46): 6080-6081.

DOI：10.1016/j.tetlet.2011.09.003

• Acrylates
• Dimethylformamide
• Ketene acetals
• New synthetic method
• Vilsmeier reagent

A highly stereoselective one-step method for the synthesis of alkyl (E)-(3-dimethylamino)acrylates from N,N-dimethylformamide and ketene acetals is reported.

• 出版日期2011-11-16