摘要
The formation of an amide bond via incorporation of two isocyanide units during a palladium-catalyzed construction of the indoloquinoline ring afforded N-substituted 6H-indolo[2,3-b]quinoline-11-carboxamides as new cytotoxic agents. The solvent and base play a key role in the selective and unprecedented synthesis of this class of amides.
- 出版日期2016-11-3