Computerized analysis of enhancement kinetics for preoperative lymph node staging in rectal cancer using dynamic contrast-enhanced magnetic resonance imaging

作者：Vag Tibor^*; Slotta Huspenina Julia; Rosenberg Robert; Bader Franz G; Nitsche Ulrich; Drecoll Enken; Rummeny Ernst J; Gaa Jochen

来源：Clinical Imaging, 2014, 38(6): 845-849.

DOI：10.1016/j.clinimag.2014.06.011

• Lymph node
• MRI
• Rectal cancer
• CAD
• Enhancement kinetics

For this feasibility study, dynamic contrast-enhanced magnetic resonance imaging (dceMRI) was performed preoperatively in 9 patients with histologically proven rectal carcinoma. A total of 41 lymph nodes detected were matched to histopathology. Their contrast enhancement patterns were evaluated using computer-aided analysis and categorized in persistent, plateau, and washout curve type. Highest diagnostic accuracy for detecting malignancy was observed, when less than 31.8% of the voxels within a lymph node demonstrated a washout curve (sensitivity/specificity of 81.8%/89.7%; area under the curve, AUC=0.87). In comparison, conventional size measurements revealed lower AUC of 0.81 (sensitivity/specificity of 75%/72.4%). We conclude that dceMRI might be of diagnostic value for preoperative lymph node staging.

• 出版日期2014-12