Health related quality of life in Mexican women with systemic lupus erythematosus: a descriptive study using SF-36 and LupusQoL (c)

作者：Garcia Carrasco M^*; Mendoza Pinto C; Cardiel M H; Mendez Martinez S; Garcia Villasenor A; Jimenez Hernandez C; Alonso Garcia N E; Briones Rojas R; Ramos Alvarez G; Lopez Colombo A

来源：Lupus, 2012, 21(11): 1219-1224.

DOI：10.1177/0961203312456749

• Health-related quality of life
• systemic lupus erythematosus
• LupusQoL (c)
• SF-36

The LupusQoL (c) questionnaire is a disease-specific health related quality of life (HRQOL) instrument for adults with systemic lupus erythematosus (SLE). The Short Form-36 (SF-36) is a generic instrument that captures the physical, psychological, and social impact. We conducted a descriptive study of women aged >= 18 years attending our Lupus Clinic. HRQOL was assessed by applying the LupusQoL (c) and SF-36. Lupus activity was measured using the Mexican Systemic Lupus Erythematosus Disease Activity Index (Mex-SLEDAI) and chronic damage using the Systemic Lupus Collaborative Clinics Damage Index (SDI). Data were analyzed using descriptive statistics, the chi-square test and Pearson's product moment correlation coefficient. A total of 127 patients were included with a mean age of 40.5 +/- 12.6 years. The mean disease duration was 8.2 +/- 5.6 years, the mean disease activity score was 2.4 +/- 3.0, and the mean SDI score 0.77 +/- 1.06. The mean SF-36 score was 58.1 +/- 21.1 and the mean LupusQoL (c) score was 69 +/- 22.7. The correlation between global scores of the SF-36 and LupusQoL (c) was rho 0.73 (p < 0.001). The correlation between lupus disease activity and the SF-36 and the LupusQoL (c) was -0.26 (p = 0.003) and -0.25 (p = 0.004), respectively. The correlation between the SDI and the SF-36 and the LupusQoL (c) was -0.28 (p = 0.001) and -0.38 (p < 0.0001), respectively. In conclusions: both LupusQoL (c) and SF-36 were useful instruments in assessing HRQOL in Mexican lupus female patients.

• 出版日期2012-10