Pesticide exposure and chiral chemistry: the pyrethroid family

作者：Ulrich Elin M^*

来源：Chimica Oggi-Chemistry Today, 2007, 25(5): 37-39.

Advances in chiral chromatography significantly advanced the ability to analyze individual enantiomers of chiral compounds. These techniques are being employed at the U. S. EPA for human exposure and ecological research studies. Enantiomer fractions (EFs) were measured for cis-permethrin, a pyrethroid insecticide. Nonracemic EFs in some environmental samples indicate that some enantioselective biological degradation has occurred, either in the indoor environment or prior to translocation indoors. These results highlight the importance of chiral methods because some degradation pathways can change the distribution of enantiomers in the environment and may lead to differential exposure. The toxicity of enantiomers can also vary. When these two factors are combined, a differential risk to humans and other organisms may be revealed.

• 出版日期2007-9