Association Between the Visceral Adiposity Index and Homeostatic Model Assessment of Insulin Resistance in Participants With Normal Waist Circumference

作者：Ji, Baolan; Qu, Hua; Wang, Hang; Wei, Huili; Deng, Huacong^*

来源：Angiology, 2017, 68(8): 716-721.

DOI：10.1177/0003319716682120

• insulin resistance
• visceral lipid accumulation
• visceral adiposity index
• nonobese
• central obesity

We assessed the correlation between the visceral adiposity index (VAI; a useful indicator of adipose distribution and function) and homeostatic model assessment of insulin resistance (HOMA-IR) in participants with normal waist circumference. A cross-sectional study was conducted, which included 1834 Chinese adults. The blood pressure, anthropometric measurements, fasting and postprandial blood glucose, fasting insulin, and lipid profiles were measured. The VAI and HOMA-IR were calculated. Participants were divided into 4 groups according to the HOMA-IR level, and the correlation between the VAI and HOMA-IR was analyzed. The VAI gradually increased across the HOMA-IR quartiles (P < .05), and a Pearson correlation analysis showed that VAI was positively related to the HOMA-IR (P < .001) in males and females. After adjusting for the other covariates, VAI was independently correlated with the HOMA-IR. A logistic regression analysis indicated that VAI elevation was the main risk factor for the increased HOMA-IR in both genders. Overall, the VAI was closely correlated with the HOMA-IR in a population without central obesity.

• 出版日期2017-9
• 单位重庆医科大学