A Summary of Computational Resources for Protein Phosphorylation

作者：Xue, Yu^*; Gao, Xinjiao; Cao, Jun; Liu, Zexian; Jin, Changjiang; Wen, Longping; Yao, Xuebiao; Ren, Jian

来源：Current Protein & Peptide Science, 2010, 11(6): 485-496.

DOI：10.2174/138920310791824138

• Phosphorylation
• post-translational modification
• kinase-specific
• phospho-binding motif
• phosphorylation network

Protein phosphorylation is the most ubiquitous post-translational modification (PTM), and plays important roles in most of biological processes. Identification of site-specific phosphorylated substrates is fundamental for understanding the molecular mechanisms of phosphorylation. Besides experimental approaches, prediction of potential candidates with computational methods has also attracted great attention for its convenience, fast-speed and low-cost. In this review, we present a comprehensive but brief summarization of computational resources of protein phosphorylation, including phosphorylation databases, prediction of non-specific or organism-specific phosphorylation sites, prediction of kinase-specific phosphorylation sites or phospho-binding motifs, and other tools. The latest compendium of computational resources for protein phosphorylation is available at: http://gps.biocuckoo.org/links.php

• 出版日期2010-9
• 单位中山大学; 华中科技大学; 中国科学技术大学