Antibodies to Borna Disease Virus in Children with Attention Deficit-Hyperactivity Disorder Borna disease virus serology in Attention Deficit-Hyperactivity Disorder

作者：Ozcan Ozlem^*; Gungor Serdal; Helps Chris R; Turan Nuri; Tabel Yilmaz; Saget Hasan; Yilmaz Hueseyin

来源：Neurology Psychiatry and Brain Research, 2009, 16(1): 5-8.

• Borna disease virus
• attention deficit hyperactivity disorder
• serology

Borna disease virus (BDV) causes behavioral disorders in rats infected in the newborn period. We investigated BDV serology in children with attention deficit hyperactivity disorder (ADHD).
Method: Ninety-nine children with ADHD (mean age: 8.7 +/- 2.5) and 104 control children (mean age: 8.4 +/- 2.8) were included in the study. All sera were investigated using the Enzyme-Linked Immunosorbent Assay (ELISA) method for BDV antibodies.
Results: The rate of sero-positivity was 2% (2 of 99) in ADHD and 3.8% (4 of 104) in the control group. There was no significant difference between ADHD and control group for BDV sero-positivity.
Conclusion: Our results do not support a role of BDV infections in the pathogenesis of ADHD.

• 出版日期2009