Additive-Free Chemoselective Acylation of Amines

作者:Temperini Andrea*; Terlizzi Raffaella; Testaferri Lorenzo; Tiecco Marcello
来源:Synthetic Communications, 2010, 40(2): 295-302.
DOI:10.1080/00397910902978007

摘要

Aliphatic and aromatic amines are efficiently acylated by acetic, pivalic, benzoic, phthalic, or maleic anhydrides in ethyl acetate at room temperature. Under the same experimental conditions, amino alcohols are chemoselectively acylated at the amino group.

  • 出版日期2010