Direct transition metal-free C-S bond formation: synthesis of 2-aminobenzothiazole derivatives via base-mediated approach

作者：Wang Rui^*; Chen Zhi; Yue Liang; Pan Wei; Zhao Jun Jie

来源：Tetrahedron Letters, 2012, 53(34): 4529-4531.

DOI：10.1016/j.tetlet.2012.06.034

• 2-Aminobenzothiazoles
• Transition metal-free
• Base
• DABCO
• S-Arylation

A general, efficient, and more practical protocol for the base-mediated intermolecular or intramolecular S-arylation leading to the 2-aminobenzothiazole derivatives is reported. Remarkably, all reactions were carried out under transition-metal-free conditions with good to excellent yields, rendering the methodology presented herein highly valuable from both environmental and economic points of view.

• 出版日期2012-8-22
• 单位重庆理工大学