Mitochondrial replacement approaches: challenges for clinical implementation

Klopstock Thomas<sup>*</sup>; Klopstock Barbara; Prokisch Holger

doi:10.1186/s13073-016-0380-2

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Mitochondrial replacement approaches: challenges for clinical implementation

作者：Klopstock Thomas^*; Klopstock Barbara; Prokisch Holger

来源：Genome Medicine, 2016, 8(1): 126.

DOI：10.1186/s13073-016-0380-2

摘要

The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.