A spectroscopic study of the bromination of the endocrine disruptor ethynylestradiol

作者：Lu Junhe; Korshin Gregory V^*

来源：Chemosphere, 2008, 72(3): 504-508.

DOI：10.1016/j.chemosphere.2008.02.055

• ethynylestradiol
• bromination
• kinetics
• fluorescence
• absorbance

Bromination of ethynylestradiol (EE2) was studied using fluorescence and conventional and stopped-flow absorbance spectroscopy. EE2 transformations in the presence of bromine were determined to proceed through sequential reactions. The first step is very rapid and results in the formation of a brominated cyclohexadienone that is susceptible to reduction but in oxidative conditions it undergoes a transformation into monobromo-EE2 in a first-order OH--accelerated reaction. The transformation from monobromo-EE2 to dibromo-EE2 follows a similar mechanism. The rates of reactions of bromine-substituted EE2 species are orders of magnitude lower than that of the parent compound indicating that these species can persist in conditions typical for water treatment operations.

• 出版日期2008-6