New antibiotic with typical plant anthraquinone structure obtained studying terrestrial and marine Streptomycetes

作者：Cui Hong Xia; Shaaban Khaled A; Schiebel Mirko; Qin Song^*; Laatsch Hartmut

来源：WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2008, 24(3): 419-421.

DOI：10.1007/s11274-007-9477-5

• Streptomycetes
• 1,6-dihydroxy-8-hydroxymethyl-anthraquinone
• 1-hydroxy-6-methoxy-8-methyl-anthraquinone
• aloesaponarin II

In our screening for new antibiotics from bacteria, the streptomycete isolate M097 from Jiaozhou Bay in China was found to produce aloesaponarin II (1a) and 1,6-dihydroxy-8-hydroxymethyl-anthraquinone (2). Similarly, a terrestrial streptomycete GW24/1694 produced 1a and its methyl ether, the new compound 1-hydroxy-6-methoxy-8-methyl-anthraquinone (1b). All structures were derived by spectrochemical analysis and by comparison with reference data. The results showed that the marine streptomycete isolate M097 and the terrestrial streptomycete GW24/1694 could be a promising material for studying the biosynthetic pathway of polyketides.

• 出版日期2008-3
• 单位燕山大学; 中国科学院海洋研究所