A Comparative Study on the Sensitive Detection of Hydroxyl Radical Using Thiol-capped CdTe and CdTe/ZnS Quantum Dots

作者：Adegoke Oluwasesan; Nyokong Tebello^*

来源：Journal of Fluorescence, 2012, 22(6): 1513-1519.

DOI：10.1007/s10895-012-1089-2

• Hydroxyl radical
• Quantum dots
• Mercaptopropionic acid
• Thioglycolic acid
• Glutathione

Four types of water-soluble luminescent quantum dots (QDs) whose surface was functionlaized with thioglycolic acid (TGA), 3-mercaptopropionic acid (MPA), or glutathione (GSH), were investigated for the sensitive and selective detection of hydroxyl radical ((OH)-O-au) in aqueous media. It was found that the type of capping agent and QD influenced the sensitivity of the probe. The order of sensitivity of the probe was: GSH-CdTe@ZnS > MPA-CdTe@ZnS > TGA-CdTe > MPA-CdTe QDs. Under the optimum conditions, a limit of detection as low as 8.5 x 10(-8) M was obtained using GSH-CdTe@ZnS. The effects of foreign reactive oxygen species and the Fenton reactants and products as possible interferences on the proposed probe were negligible for CdTe@ZnS QDs. Besides, experimental results indicated that CdTe@ZnS QDs were more attractive for the selective recognition of (OH)-O-au than CdTe QDs. The mechanistic reaction pathway between the QDs and (OH)-O-au is proposed.

• 出版日期2012-11