科研之友
微信
新浪微博
Facebook
分享链接
摘要
We report herein an atom- economical and sustainable approach to access amidinyl radical intermediates through the anodic cleavage of N-H bonds. The resulting nitrogen-centered radicals undergo cyclizations with (hetero) arenes, followed by rearomatization, to afford functionalized tetracyclic benzimidazoles in a highly straightforward and efficient manner. This metal-and reagent-free C-H/N-H cross-coupling reaction exhibits a broad substrate scope and proceeds with high chemoselectivity.
- 出版日期2017-1-9
- 单位厦门大学; 中国科学院福建物质结构研究所
