Arterial stiffness as a predictor of recovery of left ventricular systolic function after acute myocardial infarction treated with primary percutaneous coronary intervention

作者：Imbalzano Egidio^*; Vatrano Marco; Mandraffino Giuseppe; Ghiadoni Lorenzo; Gangemi Sebastiano; Bruno Rosa Maria; Ciconte Vincenzo Antonio; Paunovic Nevena; Costantino Rossella; Mormina Enrico Maria; Ceravolo Roberto; Saitta Antonino; Dattilo Giuseppe

来源：International Journal of Cardiovascular Imaging, 2015, 31(8): 1545-1551.

DOI：10.1007/s10554-015-0733-8

• Arterial stiffness
• Pulse wave velocity
• Left ventricular systolic function
• Myocardial infarction
• STEMI

Left ventricular ejection fraction (LVEF) and pulse wave velocity (PWV) are acknowledged as independent risk factors in different high-risk populations. We investigated the effects of arterial stiffness on LV function at 3 and 6 months after acute myocardial infarction. Changes in LVEF were evaluated in 136 consecutive patients who were diagnosed with ST-segment elevation coronary syndrome and treated with primary percutaneous coronary intervention. Doppler guided by 2D ultrasound was used to measure carotid-femoral PWV. According to tertiles of arterial stiffness, a significant correlation between higher PWV and worse recovery in LVEF was found (3 months EF change: 9.9 +/- A 5.0 % vs 5.9 +/- A 3.4 vs 3.8 +/- A 1.6; p < 0.001 and 6 months EF change: 18.5 +/- A 7.0 % vs 11.5 +/- A 5.2 vs 7.3 +/- A 3.0; p = 0.002). In the multivariate analysis PWV showed the ability to predict the outcome in terms of EF recovery at 3 and 6 months also after any correction for age and other variables (beta = -0.566, p < 0.001). Arterial stiffening may result in a less effective recovery of LV function after acute myocardial infarction.

• 出版日期2015-12