Assessment of Risk Factors Related to Suicide Attempts in Patients With Bipolar Disorder

作者：Song Joo Yun; Yu Han Young; Kim Se Hyun; Hwang Samuel S H; Cho Hyun Sang; Kim Yong Sik; Ha Kyooseob; Ahn Yong Min^*

来源：Journal of Nervous and Mental Disease, 2012, 200(11): 978-984.

DOI：10.1097/NMD.0b013e3182718a07

• Bipolar disorder
• suicide
• risk factor
• DIGS

We compared the characteristics of patients with bipolar disorder with and without a history of suicide attempts to identify the risk factors of suicide in this disorder. Among 212 patients with bipolar disorder, 44 (21.2%) patients had histories of suicide attempts. Suicide attempters were younger and more likely to be diagnosed with bipolar II. The variables that differentiated those who did from those who did not attempt suicide included age at first contact, lifetime history of antidepressant use, major depressive episode, mixed episode, auditory hallucinations, rapid cycling, the number of previous mood episodes, age of first depressive episode, and age of first psychotic symptoms. Strong predictors of suicide attempts were younger age at onset, lifetime history of auditory hallucinations, and history of antidepressant use. Antecedent depressive episodes and psychotic symptoms predicted the first suicide attempt in patients with bipolar disorder. This study could help clinicians to understand the major risk factors of suicidal behavior in bipolar disorder.

• 出版日期2012-11