Determining Optimum Conditions for Lipase-Catalyzed Synthesis of Triethanolamine (TEA)-Based Esterquat Cationic Surfactant by a Taguchi Robust Design Method

作者：Masoumi Hamid Reza Fard; Kassim Anuar^*; Basri Mahiran; Abdullah Dzulkifly Kuang

来源：Molecules, 2011, 16(6): 4672-4680.

DOI：10.3390/molecules16064672

• Taguchi design
• optimization
• esterquat
• cationic surfactant
• biosynthesis

A Taguchi robust design method with an L(9) orthogonal array was implemented to optimize experimental conditions for the biosynthesis of triethanolamine (TEA)-based esterquat cationic surfactants using an enzymatic reaction method. The esterification reaction conversion% was considered as the response. Enzyme amount, reaction time, reaction temperature and molar ratio of substrates, [oleic acid: triethanolamine (OA:TEA)] were chosen as main parameters. As a result of the Taguchi analysis in this study, the molar ratio of substrates was found to be the most influential parameter on the esterification reaction conversion%. The amount of enzyme in the reaction had also a significant effect on reaction conversion%.

• 出版日期2011-6