Dependence of ultrasound echo decorrelation on local tissue temperature during ex vivo radiofrequency ablation

作者：Subramanian Swetha; Schmidt Daniel T; Rao Marepalli B; Mast T Douglas

来源：Physics in Medicine and Biology, 2016, 61(6): 2356-2371.

DOI：10.1088/0031-9155/61/6/2356

• echo decorrelation imaging
• ultrasound imaging
• radiofrequency ablation
• temperature monitoring

This study investigates echo decorrelation imaging, an ultrasound method for thermal ablation monitoring. The effect of tissue temperature on the mapped echo decorrelation parameter was assessed in radiofrequency ablation experiments performed on ex vivo bovine liver tissue. Echo decorrelation maps were compared with corresponding tissue temperatures simulated using the finite element method. For both echo decorrelation imaging and integrated backscatter imaging, the mapped tissue parameters correlated significantly but weakly with local tissue temperature. Receiver operating characteristic (ROC) curves were used to assess the ability of echo decorrelation and integrated backscatter to predict tissue temperature greater than 40, 60, and 80 degrees C. Significantly higher area under the ROC curve (AUROC) values were obtained for prediction of tissue temperatures greater than 40, 60, and 80 degrees C using echo decorrelation imaging (AUROC = 0.871, 0.948 and 0.966) compared to integrated backscatter imaging (AUROC = 0.865, 0.877 and 0.832).

• 出版日期2016-3-21