A transistor-based biosensor for the extraction of physical properties from biomolecules

作者：Kim Sungho; Baek David; Kim Jee Yeon; Choi Sung Jin; Seol Myeong Lok; Choi Yang Kyu^*

来源：Applied Physics Letters, 2012, 101(7): 073703.

DOI：10.1063/1.4745769

An analytical technique is proposed that uses an asymmetric double-gate field-effect transistor (FET) structure to characterize the electrical properties of biomolecules, including their permittivity and charge density. Using a simple measurement with the proposed FET structure, we are able to extract the physical properties (i.e., permittivity and charge density) of biomolecules. A reliable analytical tool for the characterization of biomolecules can be provided by the proposed FET structure without a complex measurement system. It is expected that the proposed method will be expanded into a universal analysis technique for the electrical evaluation of biomolecules in applications beyond biosensing.

• 出版日期2012-8-13