Bhc-diol as a photolabile protecting group for aldehydes and ketones

作者：Lu M; Fedoryak OD; Moister BR; Dore TM^*

来源：Organic Letters, 2003, 5(12): 2119-2122.

DOI：10.1021/ol034536b

[GRAPHICS]
6-Bromo-4-(1,2-dihydroxyethyl)-7-hydroxycoumarin (Bhc-diol) can be used under simulated physiological conditions as a photoremovable protecting group for aldehydes and ketones. The single- and two-photon-induced release of benzaldehyde, piperonal, acetophenone, and cyclohexanone is demonstrated.

• 出版日期2003-6-12