New Challenges in Detecting, Grading, and Staging Endometrial Cancer After Uterine Morcellation

作者：Rivard Colleen^*; Salhadar Alia; Kenton Kimberly

来源：Journal of Minimally Invasive Gynecology, 2012, 19(3): 313-316.

DOI：10.1016/j.jmig.2011.12.019

• Uterine morcellation
• Uterine cancer
• Cancer staging

Study Objective: To evaluate the accuracy in diagnosing endometrial disease after uterine morcellation. %26lt;br%26gt;Design: Prospective case series. %26lt;br%26gt;Setting: University medical center. %26lt;br%26gt;Patients: Five women undergoing hysterectomy without morcellation because of benign indications and 5 women with endometrial cancer. %26lt;br%26gt;Interventions: Uterine specimens were obtained from all 10 study patients. The uteri were sent for pathologic analysis, processed, and fixed according to standard protocols. A single investigator then morcellated all 10 uteri. A single pathologist blinded to specimen group reviewed each specimen. %26lt;br%26gt;Main Results: The pathologist identified endometrial cancer in 4 of 5 specimens of known cancer. The fifth specimen was interpreted as benign despite the presence of grade 1, stage IA endometrial adenocarcinoma. None of the morcellated specimens could be staged. %26lt;br%26gt;Conclusion: The increasing use of uterine morcellation will result in new challenges for gynecologic oncologists secondary to difficulty in detection, and accurate grading and staging of endometrial cancer.

• 出版日期2012-6