Methyl (3aRS,3cRS,6cSR,7RS,8RS,8aSR)-2,5-bis(4-chlorophenyl)-7,9-bis(1,3-diphen yl-1H-pyrazol-4-yl)-1,3,4,6-tetraoxododecahydro-1H-dipyrrolo[3,4-a:3 %26apos;,4 %26apos;-f]pyrrolizine-3b-carboxylate dimethylformamide disolvate: a three-dimensional hydrogen-bonded framework

作者：Quiroga Jairo; Galvez Jaime; Cobo Justo^*; Glidewell Christopher

来源：Acta Crystallographica Section C-Crystal Structure Communications, 2012, 68: O439-+.

DOI：10.1107/S0108270112039856

The racemic title dipyrrolopyrrolizine compound crystallizes from dimethylformamide as a disolvate, C55H39Cl2N7O6 center dot 2C(3)H(7)NO. None of the four fused heterocyclic rings is planar; one adopts an envelope conformation, two others adopt half-chair conformations and the fourth adopts a conformation intermediate between an envelope and a half-chair. The arrangement of the ring fusions is such as to preclude the possibility of internal mirror symmetry. The three independent molecular components are weakly linked by C-H center dot center dot center dot O hydrogen bonds, and the dipyrrolopyrrolizine molecules are linked by a combination of four C-H center dot center dot center dot O and one C-H center dot center dot center dot pi(arene) hydrogen bond to form a three-dimensional framework, from which the dimethylformamide solvent molecules are pendent. However, aromatic pi-pi stacking interactions are absent in the structure.

• 出版日期2012-11