科研之友
微信
新浪微博
Facebook
分享链接
摘要
A stability indicating HPLC method for the analysis of venlafaxine hydrochloride in its pharmaceutical dosage forms is developed employing Kromasil C-18 column, mobile phase consisted of sodium acetate buffer-acetonitrile (65:35) with UV-detection at 226 nm. The method was validated as per ICH guidelines for specificity, linearity, precision and accuracy. Forced degradation studies were performed on the bulk sample using 0.5 N HCl. 0.1 N NaOH, 33 % H2O2 and heat (50 degrees C).
- 出版日期2008-12
