Novel bis[(1,2,3-triazolyl)methyl]carborane derivatives via regiospecific copper-catalyzed 1,3-dipolar cycloaddition

作者：Ol' shevskaya Valentina A; Makarenkov Anton V; Kononova Elena G; Petrovskii Pavel V; Verbitskiy Egor V; Rusinov Gennady L; Charushin Valery N; Hey Hawkins Evamarie; Kalinin Valery N

来源：Polyhedron, 2012, 42(1): 302-306.

DOI：10.1016/j.poly.2012.05.036

• Carboranes
• Carbaboranes
• Triflates
• Azides
• Cycloaddition
• 1,2,3-Triazole carboranes

1,2-Bis(azidomethyl)-o-carborane and 1,7-bis(azidomethyl)-m-carborane, prepared from the corresponding carboranylmethyl triflates and sodium azide, were conveniently functionalized by azide-alkyne cycloaddition affording novel bis[(1,2,3-triazolyl)methyl]carborane derivatives. Regiospecificity of this process was achieved by employing copper(II) acetate hydrate. Reaction of bis[(1,2,3-triazolyl)methyl]carborane derivatives with Mel yielded 3-methyl-1,2,3-triazolium carborane salts.

• 出版日期2012-7-25