Asymmetric reductive coupling of dienes and aldehydes catalyzed by nickel complexes of spiro phosphoramidites: Highly enantioselective synthesis of chiral bishomoallylic alcohols

作者：Yang Yun; Zhu Shou Fei; Duan Hai Feng; Zhou Chang Yue; Wang Li Xin; Zhou Qi Lin^*

来源：Journal of the American Chemical Society, 2007, 129(8): 2248-+.

DOI：10.1021/ja0693183

A highly efficient nickel-catalyzed asymmetric reductive coupling of dienes and aldehydes has been realized by using bulky spirobiindane phosphoramidite ligands, affording bishomoallylic alcohols in high yields with excellent diastereoselectivities and enantioselectivities.

• 出版日期2007-2-28
• 单位南开大学