MULTICOMPONENT SYNTHESIS OF SOME BENZO, PYRIMIDO AND PYRAZOLO FUSED HETEROCYCLES USING [NMP]H2PO4 AS AN EFFICIENT REACTION MEDIUM

作者：Kumari Sudesh; Khurana J M^*

来源：Indian Journal of Heterocyclic Chemistry, 2015, 24(4): 395-404.

An efficient synthesis of benzoxanthene, pyrimidoquinoline, pyrimidochromene and pyrazolopyridine fused heterocycles by condensation of aromatic aldehydes, 2-hydroxy-1,4-naphthoquinone/6-amino-1,3-dimethyl uracil/1,3-dimethyl barbituric acid/5-amino-3-methyl-1-phenylpyrazole and 5,5-dimethylcyclohexane-1,3-dione/5-methylcyclohexane-1,3-dione/cyclohexane-1,3-dione/cyclopentane-1,3-dione has been developed using [NMP]H2PO4 as a highly efficient reaction medium and catalyst. All the reactions proceeded smoothly and gave corresponding products in high yield after a simple workup.

• 出版日期2015-6