Comparison of MR Flow Quantification in Peripheral and Main Pulmonary Arteries in Patients After Right Ventricular Outflow Tract Surgery: A Retrospective Study

作者：Rutz Tobias^*; Meierhofer Christian; Naumann Susanne; Martinoff Stefan; Ewert Peter; Stern Heiko C; Fratz Sohrab

来源：Journal of Magnetic Resonance Imaging, 2017, 46(6): 1839-1845.

DOI：10.1002/jmri.25701

Purpose: To compare the quantification of pulmonary stroke volume (SV) by phase contrast magnetic resonance (PC-MR) in the main pulmonary artery (MPA) to the sum of SVs in both peripheral pulmonary arteries (PPA) in different right ventricular (RV) outflow pathologies.
Materials and Methods: Pulmonary SV was determined by PC-MR in the MPA and the PPA in healthy individuals (H, n = 54), patients after correction for tetralogy of Fallot with significant pulmonary regurgitation and without pulmonary or RV outflow tract stenosis (PR, n = 50), and in patients with RV outflow tract or pulmonary valve stenosis (PS, n = 50). Resulting SVs were compared to aortic SV in the ascending aorta.
Results: Mean age was similar between the groups: H 28 +/- 17 vs. PR 24 +/- 11 vs. PS 22 +/- 10 years. Bland-Altman analyses revealed in all groups a relatively small systemic (bias) but large random error (limits of agreement) for pulmonary SV determined in the MPA as compared to summed SVs in the PPA. The largest limits of agreement were present in PS patients: H: MPA 3.9% (-11, +19) vs. PPA 0.4% (-15, +15); PR: MPA 5.2% (-25, +36) vs. PPA 0.6% (-24, +26); PS: MPA 5% (-36; +46), PPA -0.03% (-34, +35).
Conclusion: The accuracy of PC-MR in the MPA is reasonable; however, a large random error (precision) is observed that is most pronounced in PS patients. This potential error should be taken into consideration when interpreting MPA flow measurements.

• 出版日期2017-12