An eco-benign and highly efficient access to dihydro-1H-indeno[1,2-b] pyridines in 2,2,2-trifluoroethanol

作者：Khaksar Samad^*; Gholami Milad

来源：Journal of Molecular Liquids, 2014, 196: 159-162.

DOI：10.1016/j.molliq.2014.03.030

• Heterocycle
• Multicomponent
• Fluorinated alcohols
• Reusable
• Hydrogen bonding

4-Aryl-4,5-dihydro-1H-indeno[1,2-b]pyridine derivatives are synthesized from both electron-deficient and electron-rich substrates in a fast, high yielding, and operationally simple protocol in 2,2,2-trifluoroethanol (TFE). The solvent (TFE) can be readily separated from reaction products and recovered in excellent purity for direct reuse.

• 出版日期2014-8