A new method to deliver breast and chest wall radiation in breast radiotherapy for lung and heart sparing

作者：Shi, Lei; He, Chunbo^*; Guo, Xu; Zhao, Lisong; Fu, Tianyi; Han, Beiqiu

来源：International Journal of Clinical and Experimental Medicine, 2016, 9(7): 13484-13492.

• Breast cancer
• radiotherapy
• toxicity

The aim of this study was to assess the efficacy of a modified irradiation technique in breast cancer patients for improving dose distribution to the target and minimizing lung and cardiac doses. Forty-two patients with breast cancer undergoing postoperative radiotherapy were included. Comparative dose planning of two techniques (WBB and CCB-TPM) was performed. Dose Volume Histogam was calculated for the PTV and organs at risk. The lung and heart received a lower dose with the CCB-TPM. The most common symptoms in the CCB-TPM group were pain and tenderness of the skin. The PTV dose coverage was comparable between the groups. CCB-TPM is well accepted and superior for left-sided breast cancer patients with respect to heart dosing and for both sides in terms of pulmonary dosing. This technique improves the dose distribution to the PTV without significantly increasing the dose to organs at risk.

• 出版日期2016
• 单位哈尔滨医科大学