A niche role for periostin and macrophages in glioblastoma

作者:Squadrito Mario Leonardo*; De Palma Michele
来源:Nature Cell Biology, 2015, 17(2): 107-109.
DOI:10.1038/ncb3095

摘要

Macrophages facilitate tumour progression, but it is unclear whether this capability is influenced by tumour-initiating cells. Glioblastoma stem cells are now shown to secrete periostin, a matrix protein that recruits protumoral macrophages and enhances glioblastoma progression in mice.

  • 出版日期2015-2