1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging

作者：Yang, Yan; Schuehle, Daniel T.; Dai, Guangping; Alford, Jamu K.; Caravan, Peter^*

来源：Contrast Media and Molecular Imaging, 2012, 7(2): 276-279.

DOI：10.1002/cmmi.490

• Chemical shift imaging
• multiplex
• gadolinium

Proton-based chemical shift imaging probes were encapsulated inside nano-carriers to increase the sensivitity of the reporters. Co-encapsulation with a relaxation agent results in improved sensitivity and suppresses background signals. Simultaneous imaging of different chemical shift reporters allows multiplexed detection.

• 出版日期2012-3
• 单位武汉大学