A review of fluorescent ligands for studying 5-HT3 receptors

作者：Lochner Martin; Thompson Andrew J

来源：Neuropharmacology, 2015, 98: 31-40.

DOI：10.1016/j.neuropharm.2015.04.002

• Fluorescent ligand
• 5-HT3 receptor
• Fluorescence polarisation
• Imaging
• Synthesis
• Flow cytometry

The use of fluorescence is a valuable and increasingly accessible means of probing the pharmacology and physiology of cells and their receptors. To date, the use of fluorescence-based methods for 5-HT3 receptor research has been quite limited and, although a variety of approaches have been described, these are broadly distributed throughout the literature. In this review we condense these findings into a single, accessible source of reference with the hope of promoting the use of these valuable molecular probes.
This article is part of the Special Issue entitled 'Fluorescent Tools in Neuropharmacology'.

• 出版日期2015-11