Using neural attention networks to detect adverse medical events from electronic health records

作者：Chu, Jiebin; Dong, Wei; He, Kunlun; Duan, Huilong; Huang, Zhengxing^*

来源：Journal of Biomedical Informatics, 2018, 87: 118-130.

DOI：10.1016/j.jbi.2018.10.002

• Adverse medical event
• Neural attention network
• Electronic health record
• Deep learning
• Cardiovascular disease

The detection of Adverse Medical Events (AMEs) plays an important role in disease management in ensuring efficient treatment delivery and quality improvement of health services. Recently, with the rapid development of hospital information systems, a large volume of Electronic Health Records (EHRs) have been produced, in which AMEs are regularly documented in a free-text manner. In this study, we are concemed with the problem of AME detection by utilizing a large volume of unstructured EHR data. To address this challenge, we propose a neural attention network-based model to incorporate the contextual information of words into AME detection. Specifically, we develop a context-aware attention mechanism to locate salient words with respect to the target AMEs in patient medical records. And then we combine the proposed context attention mechanism with the deep learning tactic to boost the performance of AME detection. We validate our proposed model on a real clinical dataset that consists of 8845 medical records of patients with cardiovascular diseases. The experimental results show that our proposed model advances state-of-the-art models and achieves competitive performance in terms of AME detection.

• 出版日期2018-11
• 单位浙江大学; 中国人民解放军总医院