Drug-induced lupus erythematosus tumidus during treatment with adalimumab

作者:Sohl S*; Renner R; Winter U; Bodendorf M; Paasch U; Simon J C; Treudler R
来源:Hautarzt, 2009, 60(10): 826-829.
DOI:10.1007/s00105-008-1699-4

摘要

Patients treated with TNF-alpha inhibitors frequently have serum autoantibodies, but only a few develop clinically apparent lupus erythematosus. The TNF-alpha inhibitor adalimumab is a fully humanized antibody and seems to induce autoantibodies less frequently than other drugs of this group. We report on a patient with rheumatoid arthritis, who developed anti-histone antibodies and lupus tumidus after eight months on adalimumab therapy.

  • 出版日期2009-10