A simple and efficient one-step synthesis of 3-substituted-4-hydroxyquinolin-2-one derivatives

作者：Toum Jerome; Moquette Alexandre; Lamotte Yann; Mirguet Olivier^*

来源：Tetrahedron Letters, 2012, 53(15): 1920-1923.

DOI：10.1016/j.tetlet.2012.01.140

• 4-Hydroxyquinolinone
• Quinolinone
• Cyclization
• One-step procedure

A new simple and efficient one-step procedure for the preparation of 3-substituted-4-hydroxyquinolin-2-one derivatives was developed. Product isolation is simple, isolated yields are good to excellent and this method tolerates a variety of substitution patterns.

• 出版日期2012-4-11