Nanoscale self assembly of cyclodextrin capped 4-aminobenzophenone via non-covalent interactions

作者：Rajendiran N^*; Sankaranarayanan R K

来源：Journal of Molecular Liquids, 2015, 206: 218-227.

DOI：10.1016/j.molliq.2015.02.023

• Cyclodextrin
• 4-Aminobenzophenone
• Inclusion complex
• Self-assembly
• Nanostructures
• Molecular modeling

Formation of nanoscale self-assemblies of 4-aminobenzophenone (4ABP) with alpha-CD and beta-CD was analyzed by spectral and morphological techniques. 4ABP:CD inclusion complexes are analyzed by SEM, TEM, FT-IR, DSC, XRD, and H-1 NMR methods. TEM images show that both 4ABP:alpha-CD and 4ABP:beta-CD inclusion complexes formed nanovesides and nanorods respectively. Upfield chemical shift observed for 'A' ring protons reveals that phenyl ring (without amino group substitution-ring) entered into the CD cavities and the aniline ring of 4ABP present in the exterior part of the CD cavities. Absorbance and emission fluorescence spectral shifts of 4ABP with alpha-CD and beta-CD indicate the formation of supramolecular assemblies in an aqueous solution. The spectral results shows that (i) 4ABP is partially incorporated into the CD nanocavities and (ii) "A" ring of 4ABP is deeply presentin the beta-CD cavity than in alpha-CD. Molecular modeling offered better approaching of the noncovalent interactions on the inclusion complex 4ABP:CDs. The negative Delta H and Delta S values specified that the inclusion process was an exothermic and thermodynamically much favorable.

• 出版日期2015-6