Basic ionic liquid: A reusable catalyst for Knoevenagel condensation in aqueous media

作者:Gao Guo hua*; Lu Liang; Zou Ting; Gao Jin bao; Liu Ye; He Ming yuan
来源:Chemical Research in Chinese Universities, 2007, 23(2): 169-172.
DOI:10.1016/S1005-9040(07)60035-X

摘要

An efficient, environmentally friendly procedure was developed for the condensation of aldehydes/ketones and activated methylene compounds with basic ionic liquid as the catalyst in water. This basic ionic liquid catalyst has a very high activity for Knoevenagel condensation to give the corresponding products in 70%-97% isolated yields under mild conditions. The basic ionic liquid catalyst in aqueous system can be reused for six times without any significant loss of activity.