A cooperative fast annealing coevolutionary algorithm for protein motif extraction

作者：Chen Chao; Tian YuanXin; Zou XiaoYong^*; Cai PeiXang; Mo JinYuan

来源：Chinese Science Bulletin, 2007, 52(3): 318-323.

DOI：10.1007/s11434-007-0047-x

• global optimization
• cooperative approach
• fast annealing
• evolutionary algorithm
• protein motif

By integrating the cooperative approach with the fast annealing coevolutionary algorithm (FAEA), a so-called cooperative fast annealing coevolutionary algorithm (CFACA) is presented in this paper for the purpose of solving high-dimensional problems. After the partition of the search space in CFACA, each smaller one is then searched by a separate FAEA. The fitness function is evaluated by combining sub-solutions found by each of the FAEAs. It demonstrates that the CFACA outperforms the FAEA in the domain of function optimization, especially in terms of convergence rate. The current algorithm is also applied to a real optimization problem of protein motif extraction. And a satisfactory result has been obtained with the accuracy of prediction achieving 67.0%, which is in agreement with the result in the PROSITE database.

• 出版日期2007-2
• 单位中山大学