Amberlyst 15 as a mild and effective activator for the glycosylation with disarmed glycosyl trichloroacetimidate donors

作者：Tian Qiang; Zhang Shuo; Yu Qian; He Mei Bo; Yang Jin Song^*

来源：Tetrahedron, 2007, 63(10): 2142-2147.

DOI：10.1016/j.tet.2006.12.091

• Amberlyst 15
• glycosylation
• trichloroacetimidate
• oligosaccharide

Amberlyst 15 acidic resin has been shown to be a mild and effective activator for the glycosylation with commonly used disarmed glycosyl trichloroacetimidate donors. Glucosylation, galactosylation, rhamnosylation, and lactosylation of a panel of representative alcohol and thiol acceptors promoted by Amberlyst 15 allowed for the formation of structurally diverse O- or S-linked oligosaccharides and glycosylated amino acids in moderate to excellent yields.

• 出版日期2007-3-5
• 单位四川大学