Arginine-pyrimidine conjugates with therapeutic and prophylactic activity in lethal bacterial infections

作者：Haebich Dieter^*; Kroll Hein Peter; Lerchen Hans Georg

来源：Bioorganic & Medicinal Chemistry Letters, 2009, 19(22): 6217-6318.

DOI：10.1016/j.bmcl.2009.09.090

• Antibacterials
• Host-pathogen interaction
• Immunostimulant
• Signal transduction

Arginine-pyrimidine conjugates represent a novel class of compounds that exhibits therapeutic and prophylactic activity in lethal infections by Gram-positive and Gram-negative bacteria without showing antibacterial activity in vitro.

• 出版日期2009-11-15