Absolute configuration of odorine

作者:Fun Hoong Kun*; Chantrapromma Suchada; Yodsaoue Orapun; Karalai Chatchanok
来源:Acta Crystallographica Section E-Structure Reports Online, 2010, 66: O2437-U1380.
DOI:10.1107/S1600536810034227

摘要

The title compound, known as odorine or roxburghiline {systematic name: (S)-N-[(R)-1-cinnamoylpyrrolidin-2-yl]-2-methylbutanamide}, C(18)H(24)N(2)O(2), is a nitrogenous compound isolated from the leaves of Aglaia odorata. The absolute configuration was determined by refinement of the Flack parameter with data collected using Cu K alpha radiation showing positions 2 and 2' to be S and R, respectively. The pyrrolidine ring adopts an envelope conformation. In the crystal, molecules are linked into chains along [010] by intermolecular N-H center dot center dot center dot O hydrogen bonds.

  • 出版日期2010-9

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