A Ribosomal Perspective on Proteostasis and Aging

作者:Steffen Kristan K; Dillin Andrew
来源:Cell Metabolism, 2016, 23(6): 1004-1012.
DOI:10.1016/j.cmet.2016.05.013

摘要

As the first and most direct process influencing the proteostasis capacity of a cell, regulation of translation influences lifespan across taxa. Here we highlight some of the newly discovered means by which translational regulation affects cellular proteostasis, with a focus on mechanisms that may ultimately impinge upon the aging process.

  • 出版日期2016-6-14