PAMAM dendrimers as supramolecular hosts through non-covalent interactions

作者：Jolly Ashley M; Bonizzoni Marco^*

来源：Supramolecular Chemistry, 2015, 27(3): 151-160.

DOI：10.1080/10610278.2014.915971

• electrostatics
• fluorescence
• polyelectrolytes
• cation-pi
• dendrimers

This manuscript reports on the binding of fluorescent polyanionic probes to various generations of amine-terminated poly(amidoamine) dendrimers (G3-G6) in buffered aqueous media, monitored through optical spectroscopy. These binding processes were used as a tool to investigate how structural features of the guest (e.g. charge, electronic structure and hydrophobicity) influence the binding process. Our results provide an initial understanding of the nature of the fundamental intermolecular interactions involved when these interesting highly regular water-soluble hyperbranched polymers function as supramolecular hosts. Electrostatics was found to be the major driver of the binding process, but solvation effects and cation-pi interactions also play a significant role in these processes.

• 出版日期2015-3-4