A FACILE SYNTHESIS OF 3-(5-CHLORO-1-PHENYL-1H-BENZO [d] IMIDAZOL-2(3H)-YLIDENEAMINO)-2-ARYLTHIAZOLIDIN-4-ONES, 3-ARYL-11,2,4] TRIAZINO [4,3-a]-5-SUBSTITUTEDBENZIMIDAZOL-4-ONES AND 1-(5-CHLORO-1-PHENYL-1H-BENZO [d] IMIDAZOL-2(3H)-YLIDENEAMINO)-3-CHLORO-4-ARYLAZETIDIN-2-ONES

作者：Mallaiah B; Laxminarayana E^*; Giri T; Chary M Thirumala

来源：Indian Journal of Heterocyclic Chemistry, 2014, 24(2): 181-184.

5-Chloro-1H-benzo [d] imidazol-2(3H)-one (1) reacts with hydrazine hydrate to give 5-chloro-1-(1H-benzo [d] imidazol-2(3H)-ylidene) hydrazine (2) which on condensation with aromatic aldehydes offered 1-(5-chloro-1-phenyl-1H-benzo [d] imidazol-2(3H)ylidene)-2-arylidenehydrazines (3a-e). Compounds 3a-e were cyclised with thioglycolic acid and chloroacetylchloide to produce 3-(5-chloro-1-phenyl-1H-benzo [d] imidazol2(3H)-ylideneamino)-2-arylthiazolidin-4-ones (4a-e) and 1-(5-chloro-1-phenyl-1H-benzo [d] imidazol-2(314)-ylideneamino)-3-chloro-4-arylazetidin-2-ones (6a-e) respectively. Compound 2 was also cyclised with aryloxoacetic acid to form 3-aryl-[1,2,4] triazino [4,3-4-5-substituted-1-phenyl-1H-benzimidazol-4-ones (5a-e).

• 出版日期2014-12