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摘要
A simple and efficient synthetic route to 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid is described by a direct oxidation reaction of adamantan-1-yl-ethan-1-one which could be prepared by a Grignard reaction. In this approach, the oxidation reaction introduced the hydroxyl and carboxyl group by a one-pot reaction.
- 出版日期2013-12
- 单位上海应用技术大学
