Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing

作者:Mongkolrattanothai Kanok****; Naccache Samia N; Bender Jeffrey M; Samayoa Erik; Pham Elizabeth; Yu Guixia; Bard Jennifer Dien; Miller Steve; Aldrovandi Grace; Chiu Charles Y*
来源:Journal of the Pediatric Infectious Diseases Society, 2017, 6(4): 393-398.
DOI:10.1093/jpids/piw066

摘要

A diagnosis of brucellosis can be difficult because routine culture and serological methods exhibit variable sensitivity and specificity. We present the use of a metagenomic next-generation sequencing assay to diagnose a case of neurobrucellosis from cerebrospinal fluid, resulting in the institution of appropriate antibiotic treatment and a favorable clinical outcome.

  • 出版日期2017-12