A Short Synthesis of the Triazolopyrimidine Antibiotic Essramycin

作者:Battaglia Ugo; Moody Christopher J*
来源:Journal of Natural Products, 2010, 73(11): 1938-1939.
DOI:10.1021/np100298m

摘要

A short synthesis of the 1,2,4-triazolo[1,5-a]pyrimidine antibiotic essramycin is described involving condensation of aminoguanidine with ethyl benzoylacetate to give an amino-1,2,4-triazole, followed by condensation with ethyl acetoacetate to form the pyrimidone ring.

  • 出版日期2010-11